COM March 2009 Diagnosis UW School of Dentistry melanotic macule or non cancerous hyperpigmentation of a mucous? What is this? Pigmentation? Hlp : r askdentists Simple cryosurgical treatment of the oral melanotic macule ScienceDirect Tiny brown spot on the lip? Don't ignore it. A melanotic macule is a small, well circumscribed brown to black oral lesion most commonly seen on the lower lip and a high yield ADC exam favourite. Variations of oral anatomy and common oral lesions Anais Brasileiros de Dermatologia (Portuguese)