Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors Tylenol: How much is too much of a good thing? Allied Medical Training Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Your liver's unsung hero: Glutathione Let's talk about what really happens when you take Tylenol (acetaminophen). Your liver breaks down acetaminophen through several pathways. One pathway creates NAPQIa reactive compound that needs Tylenol's Impact on Glutathione and Liver Damage